作者: Juan Alvarez , Heather C. Losey , Jean Chamoun
DOI:
关键词: Mucin 、 Active protein 、 Covalent bond 、 Domain (software engineering) 、 Fusion 、 Biochemistry 、 Fusion protein 、 Chemistry
摘要: The present invention provides fusion proteins comprising a mucin-domain polypeptide covalently linked to an active protein that has improved properties (e.g. pharmacokinetic and/or physicochemical properties) compared the same not polypeptide, as well methods for making and using of invention.