Ovarian carcinomas: five distinct diseases with different origins, genetic alterations, and clinicopathological features

作者: Jaime Prat

DOI: 10.1007/S00428-012-1203-5

关键词: Serous fluidOvarian carcinomaCarcinogenesisFallopian tubeKRASPathologyBiologyOvaryClear cellMolecular pathologyPathology and Forensic MedicineCell biologyMolecular biologyGeneral Medicine

摘要: … ovarian cancers and also the most lethal gynecological malignancies. Based on histopathology and molecular genetic alterations, ovarian … in epidemiological and genetic risk factors, …

参考文章(87)
Carlos Gamallo, José Palacios, Gema Moreno, Jorge Calvo de Mora, Asunción Suárez, Alvaro Armas, β-Catenin Expression Pattern in Stage I and II Ovarian Carcinomas : Relationship with β-Catenin Gene Mutations, Clinicopathological Features, and Clinical Outcome American Journal of Pathology. ,vol. 155, pp. 527- 536 ,(1999) , 10.1016/S0002-9440(10)65148-6
Georgia Chenevix-Trench, Andrew Hitchcock, Eric J. Thomas, Sarah J. Morland, Ian G. Campbell, Richard H. Watson, Koshiro Obata, Frequent PTEN/MMAC mutations in endometrioid but not serous or mucinous epithelial ovarian tumors. Cancer Research. ,vol. 58, pp. 2095- 2097 ,(1998)
Miriam Cuatrecasas, Alberto Villanueva, Xavier Matias‐Guiu, Jaime Prat, None, K-ras mutations in mucinous ovarian tumors : A clinicopathologic and molecular study of 95 cases Cancer. ,vol. 79, pp. 1581- 1586 ,(1997) , 10.1002/(SICI)1097-0142(19970415)79:8<1581::AID-CNCR21>3.0.CO;2-T
P. Kleihues, B. W. Stewart, World Cancer Report ,(2003)
Kenneth R. Lee, Robert E. Scully, Mucinous Tumors of the Ovary The American Journal of Surgical Pathology. ,vol. 24, pp. 1447- 1464 ,(2000) , 10.1097/00000478-200011000-00001
David M. Gershenson, Charlotte C. Sun, Karen H. Lu, Robert L. Coleman, Anil K. Sood, Anais Malpica, Michael T. Deavers, Elvio G. Silva, Diane C. Bodurka, Clinical behavior of stage II-IV low-grade serous carcinoma of the ovary. Obstetrics & Gynecology. ,vol. 108, pp. 361- 368 ,(2006) , 10.1097/01.AOG.0000227787.24587.D1
Julia Willner, Kaitlyn Wurz, Kimberly H. Allison, Vijaya Galic, Rochelle L. Garcia, Barbara A. Goff, Elizabeth M. Swisher, Alternate molecular genetic pathways in ovarian carcinomas of common histological types. Human Pathology. ,vol. 38, pp. 607- 613 ,(2007) , 10.1016/J.HUMPATH.2006.10.007
Barbara M. Norquist, Rochelle L. Garcia, Kimberly H. Allison, Chris H. Jokinen, Lauren E. Kernochan, Catherine C. Pizzi, Bethany J. Barrow, Barbara A. Goff, Elizabeth M. Swisher, The Molecular Pathogenesis of Hereditary Ovarian Carcinoma: Alterations in the Tubal Epithelium of Women with BRCA1 and BRCA2 Mutations Cancer. ,vol. 116, pp. 5261- 5271 ,(2010) , 10.1002/CNCR.25439