Blood-Stage Malaria Parasite Antigens: Structure, Function, and Vaccine Potential.
作者： Nichole D. Salinas , Wai Kwan Tang , Niraj H. Tolia
DOI: 10.1016/J.JMB.2019.05.018
关键词: Global health 、 Biology 、 Disease 、 Antigen 、 Malaria 、 Parasite hosting 、 Plasmodium 、 Immunology 、 Antibody 、 Malaria vaccine
摘要: Plasmodium parasites are the causative agent of malaria, a disease that kills approximately 450,000 individuals annually, with majority deaths occurring in children under age 5 years and development malaria vaccine is global health priority. undergo complex life cycle requiring numerous diverse protein families. The blood stage parasite results clinical manifestation disease. A disrupts highly desired will aid control malaria. comprises multiple steps: invasion of, asexual growth within, egress from red cells. This review focuses on blood-stage antigens emphasis antigen structure, function, neutralizing antibodies, potential.
sci-hub.se 参考文章(198)
, Efficacy and Safety of the RTS,S/AS01 Malaria Vaccine during 18 Months after Vaccination: A Phase 3 Randomized, Controlled Trial in Children and Young Infants at 11 African Sites PLoS Medicine. ,vol. 11, pp. e1001685- ,(2014) , 10.1371/JOURNAL.PMED.1001685
Hong Liang, B Kim Lee Sim, Conservation of structure and function of the erythrocyte-binding domain of Plasmodium falciparum EBA-1751Note: Nucleotide sequence data reported in this paper are available in the Genbank™ data base under the following accession numbers: 105 (U27384); 106/10 (U27385); 7G8 (UU27386); DIV30 (U27388); FCB (U27389); FVO (U27390); HB3 (U27391); ItDR (U27392); T2/C6 (U27394); Thai436 (U27395); VI-S (U27396); W2 (U27397), 3D7 (NIH) U78724; 3D7 (NAVY) U78725.1 Molecular and Biochemical Parasitology. ,vol. 84, pp. 241- 245 ,(1997) , 10.1016/S0166-6851(96)02791-0
Peter G. Kremsner, Ayôla Akim Adegnika, Saadou Issifou, Bertrand Lell, Selidji Todagbe Agnandji, Emmanuel B. Bache, Benjamin Gottlieb Mordmüller, José Francisco Fernandes, Abraham Sunday Alabi, Béatrice Peggy Abossolo, Marguerite M. Loembe, Anita Lumeka Kabwende, Efficacy and safety of RTS,S/AS01 malaria vaccine with or without a booster dose in infants and children in Africa: final results of a phase 3, individually randomised, controlled trial. The Lancet. ,vol. 386, pp. 31- 45 ,(2015) , 10.15496/PUBLIKATION-6508
Vahideh Valizadeh, Sedigheh Zakeri, Akram A Mehrizi, Sedigheh Mirkazemi, Navid D Djadid, None, Natural acquired inhibitory antibodies to Plasmodium vivax Duffy binding protein (PvDBP-II) equally block erythrocyte binding of homologous and heterologous expressed PvDBP-II on the surface of COS-7 cells. Medical Microbiology and Immunology. ,vol. 205, pp. 85- 95 ,(2016) , 10.1007/S00430-015-0429-7
Sunetra Gupta, Robert W. Snow, Christl A. Donnelly, Kevin Marsh, Chris Newbold, Immunity to non-cerebral severe malaria is acquired after one or two infections. Nature Medicine. ,vol. 5, pp. 340- 343 ,(1999) , 10.1038/6560
Geoff Daniels, Human blood groups ,(1995)
Jennifer K. Thompson, Tony Triglia, Michael B. Reed, Alan F. Cowman, A novel ligand from Plasmodium falciparum that binds to a sialic acid-containing receptor on the surface of human erythrocytes Molecular Microbiology. ,vol. 41, pp. 47- 58 ,(2001) , 10.1046/J.1365-2958.2001.02484.X
Agata Zerka, Joanna Rydzak, Anna Lass, Beata Szostakowska, Wacław Nahorski, Agnieszka Wroczyńska, Przemyslaw Myjak, Hubert Krotkiewski, Ewa Jaskiewicz, Studies on Immunogenicity and Antigenicity of Baculovirus-Expressed Binding Region of Plasmodium falciparum EBA-140 Merozoite Ligand Archivum Immunologiae Et Therapiae Experimentalis. ,vol. 64, pp. 149- 156 ,(2016) , 10.1007/S00005-015-0367-5
M G Peterson, V M Marshall, J A Smythe, P E Crewther, A Lew, A Silva, R F Anders, D J Kemp, Integral membrane protein located in the apical complex of Plasmodium falciparum. Molecular and Cellular Biology. ,vol. 9, pp. 3151- 3154 ,(1989) , 10.1128/MCB.9.7.3151
S. Josefin Bartholdson, Cécile Crosnier, Leyla Y. Bustamante, Julian C. Rayner, Gavin J. Wright, Identifying novel Plasmodium falciparum erythrocyte invasion receptors using systematic extracellular protein interaction screens Cellular Microbiology. ,vol. 15, pp. 1304- 1312 ,(2013) , 10.1111/CMI.12151