Hydrazines and Triazenes
作者： Willi Kreis
DOI: 10.1007/978-1-4615-6628-1_17
关键词: Combinatorial chemistry 、 Biological substances 、 Cancer chemotherapy 、 Hydrazine sulfate 、 Biological activity 、 Hydrazine 、 Molecule 、 Decomposition 、 Triazene 、 Chemistry
摘要: Hydrazines, but not triazines, have been identified in a small number of biological substances. Those used cancer chemotherapy are synthetic products, relatively unstable, and provide biologically active groups on their decomposition metabolism. The basic moieties hydrazine, H2N-NH2, triazene, NH2 N=NH, substituted with aromatic aliphatic both ends nitrogen bridges; these substituents probably also limited stability to the respective molecules. While large derivatives synthesized evaluated for activity, representatives reported this chapter few, most interesting ones from therapeutic theoretical points view.
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