Pitfalls in the determination of absolute dimensions using angiographic catheters as calibration devices in quantitative angiography

摘要: Abstract Using catheter outer diameter as a scaling device, quantitative coronary arteriography allows the precise and objective measurement of change in absolute dimensions arteries after mechanical or pharmacologic intervention. Because variable density wall catheter, automated systems might vary determination diameter. To examine this premise, catheters variety French sizes from 6 manufacturers were injected with radiographic contrast used devices for arterial phantoms known geometric dimension. Radiographic diameters determined by applying arteriographic algorithm to using calibration grid same field view. The varying composition resulted differing x-ray attenuation and, subsequently, edge-detection algorithms varied widely determining actual be factor. For instance, Lucite TM “artery” minimal luminal 1.50 mm (image calibrated micrometer-determined outside Baxter 8Fr guiding catheter) angiographic 2.03 (overestimation 35%). If similar size Shiley was calibrate image, 1.60 determined: difference 0.43 based solely on differences attenuation. These data suggest that specific “finger-print” each material exists, rendering generalizations about questionable. observations are important angiography where many brands being clinically. Differences lesions could result different devices, study designs approach should take potential source error into account.