Involvement of Sphingosine‐1‐Phosphate/RhoA/Rho‐Kinase Signaling Pathway in Corporal Fibrosis Following Cavernous Nerve Injury in Male Rats
作者： Min Chul Cho , Kwanjin Park , Ji Sun Chai , Sun Hee Lee , Soo Woong Kim
DOI: 10.1111/J.1743-6109.2010.02147.X
关键词: Rho-associated protein kinase 、 RHOA 、 ROCK1 、 Endocrinology 、 Fibrosis 、 Nerve injury 、 Pathology 、 Crush injury 、 TGF beta signaling pathway 、 Kinase 、 Internal medicine 、 Medicine 、 Obstetrics and gynaecology 、 Urology 、 Reproductive medicine
摘要: … -β increases SphK1, … (SphK1) and the resulting S1P would lead to activation of the RhoA/ROCK1 pathway via S1P 2 , leading to corporal fibrosis in a rat model of CN injury (crush …
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