E-cigarettes and Urologic Health: A Collaborative Review of Toxicology, Epidemiology, and Potential Risks

作者: Farhad Islami , Hayden McRobbie , Debra T. Silverman , James W.F. Catto , Liam Bourke

DOI: 10.1016/J.EURURO.2016.12.022

关键词: Smoking cessationContext (language use)ToxicologyMedicineSystematic reviewObservational studyPublic healthEpidemiologyHealth indicatorHealth policy

摘要: Abstract Context Use of electronic cigarettes (ECs) is on the rise in most high-income countries. Smoking conventional a known risk factor for urologic malignancy incidence, progression, and mortality, as well other health indicators. The potential impact EC use therefore clinical interest to urology community. Objective To review available data current use, including benefits patients, issues linked toxicology constituents, how this might translate into risks. Evidence acquisition A Medline search was carried out August 2016 studies reporting outcomes use. Snowballing techniques were also used identify relevant from recent systematic reviews. narrative synthesis around outcomes, toxicology, smoking cessation policy out. We found no date that have been specifically designed prospectively assess risks, even an observational setting. Generating such would be important contribution debate role ECs public practice. There evidence Cochrane RCTs can support cessation. are emerging indicating potentially harmful components tobacco-specific nitrosamines, polyaromatic hydrocarbons, heavy metals could possible Conclusions useful tool encourage cigarette smoking. However, collection specific needed clarify patient benefits, adverse events. Patient summary While help some people stop smoking, their overall not clear.

参考文章(77)
S. Sean Hu, Linda Neff, Israel T. Agaku, Shanna Cox, Hannah R. Day, Enver Holder-Hayes, Brian A. King, Tobacco Product Use Among Adults - United States, 2013-2014. Morbidity and Mortality Weekly Report. ,vol. 65, pp. 685- 691 ,(2016) , 10.15585/MMWR.MM6527A1
Linda M. Liao, Melissa C. Friesen, Yong-Bing Xiang, Hui Cai, Dong-Hee Koh, Bu-Tian Ji, Gong Yang, Hong-Lan Li, Sarah J. Locke, Nathaniel Rothman, Wei Zheng, Yu-Tang Gao, Xiao-Ou Shu, Mark P. Purdue, Occupational Lead Exposure and Associations with Selected Cancers: The Shanghai Men's and Women's Health Study Cohorts. Environmental Health Perspectives. ,vol. 124, pp. 97- 103 ,(2015) , 10.1289/EHP.1408171
Man Ping Wang, Sai Yin Ho, Lok Tung Leung, Tai Hing Lam, Electronic cigarette use and its association with smoking in Hong Kong Chinese adolescents. Addictive Behaviors. ,vol. 50, pp. 124- 127 ,(2015) , 10.1016/J.ADDBEH.2015.06.037
Nan Jiang, Jing Chen, Man-Ping Wang, Sarah M. McGhee, Antonio C.S. Kwong, Vienna W.Y. Lai, Tai-Hing Lam, Electronic cigarette awareness and use among adults in Hong Kong Addictive Behaviors. ,vol. 52, pp. 34- 38 ,(2016) , 10.1016/J.ADDBEH.2015.08.008
Sarah P. Borderud, Yuelin Li, Jack E. Burkhalter, Christine E. Sheffer, Jamie S. Ostroff, Electronic cigarette use among patients with cancer: Characteristics of electronic cigarette users and their smoking cessation outcomes Cancer. ,vol. 120, pp. 3527- 3535 ,(2014) , 10.1002/CNCR.28811
Adam M. Leventhal, David R. Strong, Matthew G. Kirkpatrick, Jennifer B. Unger, Steve Sussman, Nathaniel R. Riggs, Matthew D. Stone, Rubin Khoddam, Jonathan M. Samet, Janet Audrain-McGovern, Association of Electronic Cigarette Use With Initiation of Combustible Tobacco Product Smoking in Early Adolescence JAMA. ,vol. 314, pp. 700- 707 ,(2015) , 10.1001/JAMA.2015.8950
Maciej L. Goniewicz, Peter Hajek, Hayden McRobbie, Nicotine content of electronic cigarettes, its release in vapour and its consistency across batches: regulatory implications Addiction. ,vol. 109, pp. 500- 507 ,(2014) , 10.1111/ADD.12410
Delshanee Kotandeniya, Steven G. Carmella, Makenzie E. Pillsbury, Stephen S. Hecht, Combined analysis of N'-nitrosonornicotine and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol in the urine of cigarette smokers and e-cigarette users. Journal of Chromatography B. ,vol. 1007, pp. 121- 126 ,(2015) , 10.1016/J.JCHROMB.2015.10.012
Jose M Martínez-Sánchez, Marcela Fu, Juan Carlos Martín-Sánchez, Montse Ballbè, Esteve Saltó, Esteve Fernández, Perception of electronic cigarettes in the general population: does their usefulness outweigh their risks? BMJ Open. ,vol. 5, ,(2015) , 10.1136/BMJOPEN-2015-009218
B. Eastwood, M.J. Dockrell, D. Arnott, J. Britton, H. Cheeseman, M.J. Jarvis, A. McNeill, Electronic cigarette use in young people in Great Britain 2013–2014 Public Health. ,vol. 129, pp. 1150- 1156 ,(2015) , 10.1016/J.PUHE.2015.07.009