FDG uptake in non-small cell lung cancer is not an independent predictor of EGFR or KRAS mutation status: a retrospective analysis of 206 patients.
作者： Seok Mo Lee , Sang Kyun Bae , Soo Jin Jung , Chun K. Kim
DOI: 10.1097/RLU.0000000000000975
关键词: Medicine 、 Lung cancer 、 Multivariate analysis 、 Internal medicine 、 Stage (cooking) 、 Adenocarcinoma 、 Avidity 、 Imaging biomarker 、 KRAS 、 Oncology 、 Epidermal growth factor receptor
摘要: Purpose Data in the literature regarding the use of 18 F-FDG avidity of non–small cell lung cancer (NSCLC) as an imaging biomarker to predict the status of epidermal growth factor receptor (EGFR) mutation are conflicting. Association between KRAS mutation and FDG avidity of NSCLC on PET/CT is not well known. We assessed whether the EGFR or KRAS mutation status in NSCLC can be predicted by FDG avidity by performing several different subgroup analyses to better compare with various published results. Patients and Methods …
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