Coffee Consumption and Risk of Gastric Cancer: An Updated Meta-Analysis
作者： Yan Xie , Shifeng Huang , Tongchuan He , Yuxi Su , None
关键词: Cohort 、 Operations management 、 Population 、 Relative risk 、 Cohort study 、 Meta-analysis 、 Internal medicine 、 Case-control study 、 Medicine 、 Confidence interval 、 Risk factor
摘要: Purpose: Coffee is one of the most widely consumed beverages worldwide, and many studies have investigated association between coffee consumption gastric cancer. However, results are inconsistent. We conducted a systematic analysis relevant population to derive more precise estimation. Methods: Cochrane library, PubMed Embase databases were searched identify that met predetermined inclusion criterion through July 2014. All epidemiologic regarding cancer risk selected, relative risks (RRs) with 95% confidence intervals (CIs) calculated. Results: Twenty two (9 cohort 13 case-control studies) involving 7,631 cases 1,019,693 controls included. The summary RR was 0.94 (95% CI: 0.80-1.10) for highest category compared lowest category, 0.93 0.88-0.99) drinkers nondrinkers. stratified by consumption. pooled ＜1 cup/day, 1-2 cups/day 3-4 nondrinkers 0.95 0.84-1.08), 0.92 0.82-1.03) 088 0.76-1.02), respectively, indicating an increase in associated decreased Furthermore, we design, sex, time. A significant intake shown (RR=0.85, 0.77-0.95) among published over last ten years (RR=0.88, 0.77-1.00). Conclusions: Our meta-analysis suggested might be
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