DNA sequence similarity recognition by hybridization to short oligomers

作者: Aleksandar Milosavljevic

DOI:

关键词: Nucleic acidSimilarity (network science)DNA sequencingBiologyComputational biologyData compressionMutual informationReference genomeBiochemistryDNASequence (biology)

摘要: Methods are disclosed for the comparison of nucleic acid sequences. Data is generated by hybridizing sets oligomers with target acids. The data thus manipulated simultaneously respect to both (i) matching between and (ii) putative reference sequences available in databases. Using compression methods manipulate this mutual information, can be constructed.

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