Comparative mapping and assembly of nucleic acid sequences

作者: Aleksandar Milosavljevic

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摘要: A method for assembling nucleic acid sequence fragments is disclosed. The are assembled using information about their relative position inferred by comparison of the against a known related (FIG. 3 ). Additionally, localizes to bacterial artificial chromosomes 1 ) and determines 6 utilizes orientation, mutual distance, fragment localization chromosomes, constrain assembly process 5 ), thus resulting in more accurate requiring fewer sequencing reactions.

参考文章(12)
Eugene W Myers, Granger G Sutton, Art L Delcher, Ian M Dew, Dan P Fasulo, Michael J Flanigan, Saul A Kravitz, Clark M Mobarry, Knut HJ Reinert, Karin A Remington, Eric L Anson, Randall A Bolanos, Hui-Hsien Chou, Catherine M Jordan, Aaron L Halpern, Stefano Lonardi, Ellen M Beasley, Rhonda C Brandon, Lin Chen, Patrick J Dunn, Zhongwu Lai, Yong Liang, Deborah R Nusskern, Ming Zhan, Qing Zhang, Xiangqun Zheng, Gerald M Rubin, Mark D Adams, J Craig Venter, None, A Whole-Genome Assembly of Drosophila Science. ,vol. 287, pp. 2196- 2204 ,(2000) , 10.1126/SCIENCE.287.5461.2196
Mark S. Boguski, Eric D. Green, Jeffrey W. Touchman, Jane M. Weisemann, Peter M. Kuehl, An Effective Approach for Analyzing “Prefinished” Genomic Sequence Data Genome Research. ,vol. 9, pp. 189- 194 ,(1999) , 10.1101/GR.9.2.189
John Bouck, Webb Miller, James H. Gorrell, Donna Muzny, Richard A. Gibbs, Analysis of the Quality and Utility of Random Shotgun Sequencing at Low Redundancies Genome Research. ,vol. 8, pp. 1074- 1084 ,(1998) , 10.1101/GR.8.10.1074
Scott Schwartz, Zheng Zhang, Kelly A Frazer, Arian Smit, Cathy Riemer, John Bouck, Richard Gibbs, Ross Hardison, Webb Miller, PipMaker—A Web Server for Aligning Two Genomic DNA Sequences Genome Research. ,vol. 10, pp. 577- 586 ,(2000) , 10.1101/GR.10.4.577
Liliana Florea, Cathy Riemer, Scott Schwartz, Zheng Zhang, Nikola Stojanovic, Webb Miller, Michael McClelland, Web-based visualization tools for bacterial genome alignments Nucleic Acids Research. ,vol. 28, pp. 3486- 3496 ,(2000) , 10.1093/NAR/28.18.3486
A. L. Delcher, S. Kasif, R. D. Fleischmann, J. Peterson, O. White, S. L. Salzberg, Alignment of whole genomes Nucleic Acids Research. ,vol. 27, pp. 2369- 2376 ,(1999) , 10.1093/NAR/27.11.2369
Stephen P. A. Fodor, William J. Dower, Dennis W. Solas, Method of detecting nucleic acids ,(1996)
Patrick Onyango, Webb Miller, Jessica Lehoczky, Cheuk T Leung, Bruce Birren, Sarah Wheelan, Ken Dewar, Andrew P Feinberg, Sequence and Comparative Analysis of the Mouse 1-Megabase Region Orthologous to the Human 11p15 Imprinted Domain Genome Research. ,vol. 10, pp. 1697- 1710 ,(2000) , 10.1101/GR.161800