Accurate and fast mapping of reads to genome
作者： Sim-Jasmine Truong , Xiaoju (Max) Ma , Wei-Min Liu , Xiaoying Chen , Yan Li
DOI:
关键词: Computational biology 、 Hybrid genome assembly 、 Genetics 、 Biology 、 Mutation (genetic algorithm) 、 Genome 、 Deep sequencing 、 Fast mapping
摘要: Accurate and fast mapping of sequencing reads obtained from a targeted procedure can be provided. Once target region is selected, alternate regions the genome that are sufficiently similar to identified. If read more than an region, then determined as aligning region. The analyzed determine whether mutation exists in Accordingly, compared corresponding regions, not entire genome, thereby providing computational efficiency.
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