Part time patching treatment outcomes in children with amblyopia with and without fusion maldevelopment nystagmus: An eye movement study.

摘要: Purpose We investigated how the abnormalities of fixation eye movements (FEMs) amblyopic were linked with treatment outcomes following part-time patching therapy in children amblyopia. Methods recruited 53 patients, at least 12 months patching, and measured FEMs end treatment. Subjects classified based on FEM waveforms (those without nystagmus = 21, those fusion maldevelopment (FMN) FMN 11) clinical type amblyopia (anisometropic 18, strabismic 6, mixed 29). The such as duration receiving therapy, visual acuity stereo-acuity deficits determined. Bivariate contour ellipse area (BCEA), fast (fixational saccade/quick phases), slow (inter-saccadic drifts/slow phases) fellow analyzed. Results Anisometropic group had less residual (0.23±0.19logMAR acuity) compared to strabismic/mixed (0.36±0.26) groups (p 0.007). Treatment patients was lower (12.6±9.5months) (25.6±23.2) (29.5±20.4) 0.006). Patients better stereopsis (2.3±0.84logarcsecs) (2.6±0.84) 0.003). majority (8/11) absent stereopsis. BCEA higher greater nystagmus. No association seen Nystagmus no groups. Increased amplitude FEMs, increased position variance velocity who received longer part time amblyopia, poor Conclusions Assessment characteristics are important measures while describing instability Several associated treated therapy.