Neuromuscular Blocking Agent Cisatracurium Attenuates Lung Injury by Inhibition of Nicotinic Acetylcholine Receptor-α1.
作者： Vito Fanelli , Yasumasa Morita , Paola Cappello , Mirna Ghazarian , Bina Sugumar
DOI: 10.1097/ALN.0000000000000907
关键词: Inflammation 、 Neuromuscular Blocking Agents 、 Acetylcholine 、 Immunology 、 Cytokine 、 Nicotinic acetylcholine receptor 、 Medicine 、 Pharmacology 、 Receptor 、 Lung injury 、 Interleukin 6
摘要: Background:Neuromuscular blocking agents (NMBAs) bind the nicotinic acetylcholine receptor α1 (nAChRα1) that also contributes to inflammatory signaling. Thus, author hypothesized use of NMBA mitigates lung injury by improving ventilator synchrony and decreasing responses.Me
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