作者: Donna Goodridge , Josh Lawson , Graeme Rocker , Darcy Marciniuk , Donna Rennie
DOI: 10.2147/COPD.S9938
关键词: Population 、 COPD 、 Palliative care 、 Cohort study 、 Intensive care medicine 、 Comorbidity 、 Internal medicine 、 Hydromorphone 、 Retrospective cohort study 、 Medicine 、 Odds ratio
摘要: BACKGROUND For patients in late stages of chronic obstructive pulmonary disease (COPD), dyspnea is often refractory to conventional treatment. We know little about the use opioids ameliorating this population. In study we explored factors associated with opioid dispensation within last year life and differences for persons lung cancer or COPD. METHODS retrospective cohort used administrative health data gained from 1,035 residents Saskatchewan, Canada examine patterns community life. Factors were determined using multiple logistic regression. RESULTS When compared those cancer, fewer COPD given week life; month life, 3 months After adjusting relevant predictors, more than twice as likely fill prescriptions following: morphine (odds ratio [OR] 2.36, 95% confidence interval [CI]: 1.52-3.67); hydromorphone (OR 2.69, CI: 1.53-4.72); transdermal fentanyl 2.25, 1.28-3.98); any these 2.61, 1.80-3.80). CONCLUSION These are dispensed only a small proportion at end their lives. Future researchers could explore efficacy safety advanced COPD, whether limited justified.