Factors associated with opioid dispensation for patients with COPD and lung cancer in the last year of life: A retrospective analysis.

作者: Donna Goodridge , Josh Lawson , Graeme Rocker , Darcy Marciniuk , Donna Rennie

DOI: 10.2147/COPD.S9938

关键词: PopulationCOPDPalliative careCohort studyIntensive care medicineComorbidityInternal medicineHydromorphoneRetrospective cohort studyMedicineOdds ratio

摘要: BACKGROUND For patients in late stages of chronic obstructive pulmonary disease (COPD), dyspnea is often refractory to conventional treatment. We know little about the use opioids ameliorating this population. In study we explored factors associated with opioid dispensation within last year life and differences for persons lung cancer or COPD. METHODS retrospective cohort used administrative health data gained from 1,035 residents Saskatchewan, Canada examine patterns community life. Factors were determined using multiple logistic regression. RESULTS When compared those cancer, fewer COPD given week life; month life, 3 months After adjusting relevant predictors, more than twice as likely fill prescriptions following: morphine (odds ratio [OR] 2.36, 95% confidence interval [CI]: 1.52-3.67); hydromorphone (OR 2.69, CI: 1.53-4.72); transdermal fentanyl 2.25, 1.28-3.98); any these 2.61, 1.80-3.80). CONCLUSION These are dispensed only a small proportion at end their lives. Future researchers could explore efficacy safety advanced COPD, whether limited justified.

参考文章(28)
Winanne Downey, Maryrose Stang, Patricia Beck, William Osei, James L. Nichol, Health Services Databases in Saskatchewan John Wiley & Sons, Ltd. pp. 295- 310 ,(2007) , 10.1002/9780470059876.CH19
Catherine Exley, Robert K McKinley, Tim Stokes, David Field, Care of people dying with malignant and cardiorespiratory disease in general practice. British Journal of General Practice. ,vol. 54, pp. 909- 913 ,(2004)
David Currow, Alicia Ward, Katherine Clark, Catherine Burns, Amy Abernethy, Caregivers for people with end-stage lung disease: characteristics and unmet needs in the whole population. International Journal of Chronic Obstructive Pulmonary Disease. ,vol. 3, pp. 753- 762 ,(2008) , 10.2147/COPD.S3890
Craig D. Blinderman, Peter Homel, J. Andrew Billings, Sharon Tennstedt, Russell K. Portenoy, Symptom distress and quality of life in patients with advanced chronic obstructive pulmonary disease. Journal of Pain and Symptom Management. ,vol. 38, pp. 115- 123 ,(2009) , 10.1016/J.JPAINSYMMAN.2008.07.006
Polly Edmonds, Saffron Karlsen, Saba Khan, Julia Addington-Hall, A comparison of the palliative care needs of patients dying from chronic respiratory diseases and lung cancer Palliative Medicine. ,vol. 15, pp. 287- 295 ,(2001) , 10.1191/026921601678320278
Samy Suissa, Pierre Ernst, Serge Benayoun, Marc Baltzan, Bing Cai, Low-dose inhaled corticosteroids and the prevention of death from asthma. The New England Journal of Medicine. ,vol. 343, pp. 332- 336 ,(2000) , 10.1056/NEJM200008033430504
Richard L. ZuWallack, Margaret C. Haggerty, Paul Jones, Clinically meaningful outcomes in patients with chronic obstructive pulmonary disease. The American Journal of Medicine. ,vol. 117, pp. 49- 59 ,(2004) , 10.1016/J.AMJMED.2004.10.020
Joanne Lynn, E. Wesley Ely, Zhenshao Zhong, Kristin Landrum McNiff, Neal V. Dawson, Al Connors, Norman A. Desbiens, Michael Claessens, Ellen P. McCarthy, Living and dying with chronic obstructive pulmonary disease. Journal of the American Geriatrics Society. ,vol. 48, pp. 91- 100 ,(2000) , 10.1111/J.1532-5415.2000.TB03147.X