Impact of aerobic exercise on cognitive impairment and oxidative stress markers in methamphetamine-dependent patients
作者： Kai Zhang , Qiaoyang Zhang , Haifeng Jiang , Jiang Du , Chenglin Zhou
DOI: 10.1016/J.PSYCHRES.2018.03.032
关键词: Verbal memory 、 Methamphetamine 、 Medicine 、 Blood lipids 、 Internal medicine 、 Oxidative stress 、 Lipid peroxidation 、 Endocrinology 、 Verbal learning 、 Aerobic exercise 、 Super oxide dismutase
摘要: Abstract This study aimed to investigate whether 12-week moderate-intensity aerobic exercise has beneficial effects on oxidative stress markers in blood and cognitive functions patients who have methamphetamine dependence. Serum levels of markers, including total anti-oxidation capability, super oxide dismutase (SOD), catalase (CAT), methane dicarboxylic aldehyde (MDA), were measured at baseline (all participants) the follow-up (methamphetamine-dependent patients). CAT MDA methamphetamine-dependent (n = 68) higher than those healthy controls (n = 35) baseline. Furthermore, international shopping list (ISL) task scores significantly lower controls, indicating verbal memory deficits patients. Although there no significant interactions for all function scores, improved processing speed Of interest, attenuated a spontaneous increase serum after 12-weeks abstinence. In conclusion, this showed that with learning MDA, program may as well lipid peroxidation
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