Thioredoxin Reductase 2 (Txnrd2) Regulates Mitochondrial Integrity in the Progression of Age‐Related Heart Failure

作者: Jun Yoshioka

DOI: 10.1161/JAHA.115.002278

关键词: Age relatedHeart failureMyocyteThioredoxin reductaseMetabolismMedicineVentricular functionReactive oxygen speciesPathologyCell biologyMitochondrion

摘要: Aging is a multifactorial process that characterized by the accumulation of damaged cellular components and leads progressively to deterioration biological functions.[1][1] Recently, increased production reactive oxygen species (ROS) decreased removal oxidized proteins

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