THIS OLD HEART: CARDIAC AGING AND AUTOPHAGY

作者: Phyllis-Jean Linton , Michael Gurney , David Sengstock , Robert M. Mentzer , Roberta A. Gottlieb

DOI: 10.1016/J.YJMCC.2014.12.017

关键词: Cardiac dysfunctionRegulation of gene expressionImmunologyAutophagyInflammationBioinformaticsSignal transductionHomeostasisMitochondrionBiologyTissue homeostasis

摘要: … The activities of the ubiquitin-like proteins Atg3 and Atg7 in … Langendorff-perfused hearts from NLRP3 knockout mice had … in NLRP3 vs ASC knockouts, it is clear that the NLRP3 …

参考文章(162)
May Christine V. Malicdan, Satoru Noguchi, Ichizo Nishino, Monitoring autophagy in muscle diseases. Methods in Enzymology. ,vol. 453, pp. 379- 396 ,(2009) , 10.1016/S0076-6879(08)04019-6
F. Aniento, E. Roche, A.M. Cuervo, E. Knecht, Uptake and Degradation of glyceraldehyde-3-phosphate Dehydrogenase by Rat Liver Lysosomes Journal of Biological Chemistry. ,vol. 268, pp. 10463- 10470 ,(1993) , 10.1016/S0021-9258(18)82222-0
Borbála Pazár, Hang-Korng Ea, Sharmal Narayan, Laeticia Kolly, Nathalie Bagnoud, Véronique Chobaz, Thierry Roger, Frédéric Lioté, Alexander So, Nathalie Busso, Basic Calcium Phosphate Crystals Induce Monocyte/Macrophage IL-1β Secretion through the NLRP3 Inflammasome In Vitro Journal of Immunology. ,vol. 186, pp. 2495- 2502 ,(2011) , 10.4049/JIMMUNOL.1001284
Roberta A. Gottlieb, Autophagy in health and disease Academic Press. ,(2013)
Nilgün Gedik, Matthias Thielmann, Eva Kottenberg, Jürgen Peters, Heinz Jakob, Gerd Heusch, Petra Kleinbongard, No Evidence for Activated Autophagy in Left Ventricular Myocardium at Early Reperfusion with Protection by Remote Ischemic Preconditioning in Patients Undergoing Coronary Artery Bypass Grafting PLoS ONE. ,vol. 9, pp. e96567- ,(2014) , 10.1371/JOURNAL.PONE.0096567
Allen M. Andres, Genaro Hernandez, Pamela Lee, Chengqun Huang, Eric P. Ratliff, Jon Sin, Christine A. Thornton, Marichris V. Damasco, Roberta A. Gottlieb, Mitophagy is required for acute cardioprotection by simvastatin. Antioxidants & Redox Signaling. ,vol. 21, pp. 1960- 1973 ,(2014) , 10.1089/ARS.2013.5416
Coert J. Zuurbier, Willeke M. C. Jong, Otto Eerbeek, Anneke Koeman, Wilco P. Pulskens, Loes M. Butter, Jaklien C. Leemans, Markus W. Hollmann, Deletion of the innate immune NLRP3 receptor abolishes cardiac ischemic preconditioning and is associated with decreased Il-6/STAT3 signaling PLOS ONE. ,vol. 7, ,(2012) , 10.1371/JOURNAL.PONE.0040643
Anne Simonsen, Robert C. Cumming, Andreas Brech, Pauline Isakson, David R. Schubert, Kim D. Finley, Promoting basal levels of autophagy in the nervous system enhances longevity and oxidant resistance in adult Drosophila. Autophagy. ,vol. 4, pp. 176- 184 ,(2008) , 10.4161/AUTO.5269
Xue Wang, Xu-Lei Wang, Hua-Li Chen, Dan Wu, Jia-Xiang Chen, Xiao-Xiao Wang, Ru-Li Li, Jin-Han He, Li Mo, Xiaobo Cen, Yu-Quan Wei, Wei Jiang, Ghrelin inhibits doxorubicin cardiotoxicity by inhibiting excessive autophagy through AMPK and p38-MAPK. Biochemical Pharmacology. ,vol. 88, pp. 334- 350 ,(2014) , 10.1016/J.BCP.2014.01.040