Laboratory aspects of Lyme borreliosis.

作者: A G Barbour

DOI: 10.1128/CMR.1.4.399

关键词: BiologyVirologyChronic meningitisSerologyArthritic jointBorrelia burgdorferiMyocarditisRashLyme diseaseLyme borreliosisImmunology

摘要: Lyme borreliosis (Lyme disease), a common tick-borne disorder of people and domestic animals in North America Europe, is caused by the spirochete Borrelia burgdorferi. Following discovery initial propagation this agent 1981 came revelations that other tick-associated infectious disorders are but different forms borreliosis. A challenge for clinician microbiology laboratory confirmation skin rash, chronic meningitis, an episode myocarditis, or arthritic joint consequence B. burgdorferi infection. The diagnosis may be established (i) directly observing host fluid tissue, (ii) recovering etiologic from patient culture medium indirectly through inoculation animals, (iii) carrying out serologic tests with patient9s serum cerebrospinal fluid. last method, while lacking discriminatory power, most efficacious diagnostic assay laboratories at present. Images

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