Skin fluorescence, a method to predict amputation site healing.

摘要: Abstract Although skin blood flow is an important determinant of amputation site healing, most techniques to evaluate it are cumbersome and indirect. We have prospectively compared a new, simple direct technique, fluorescence (SF), with more established indirect method, segmental limb pressures (BP), determine the value each in predicting healing ischemic extremity. Twenty-six consecutive patients tissue loss were studied prior amputation. Thigh, calf, ankle BP measured; then SF was determined by injecting 10–15 mg/kg fluorescein intravenously examining uv light. > 50 mm Hg considered adequate for wound healing; yellow indicated flow. In case, distal predicted heal either method selected Thirty amputations performed (6 digital, 3 transmetatarsal, 11 below knee, 10 above knee) 80% rate. When disagreed on level amputation, always site. accurately cases. remaining 20%, failures due infection two deep necrosis four. accurate useful 47% 14 need higher than successfully performed. measurement indeterminate “stiff arteries.” Furthermore, failed despite Hg. conclude that helps surgeon select pressures, one has high likelihood healing.