A Straightforward Method for the Synthesis of Alkylidene and Arylidene Malonates Through Proline-Catalyzed Knoevenagel Condensation
作者： Giuliana Cardillo , Serena Fabbroni , Luca Gentilucci , Massimo Gianotti , Alessandra Tolomelli
关键词: Chemistry 、 Catalysis 、 Reagent 、 Organic chemistry 、 Proline 、 Knoevenagel condensation
摘要: Abstract A straightforward method for the synthesis of alkylidene/arylidene malonates and arylidene cyanoacetates, utilizing proline as an alternative to traditional catalysts is presented. large number unsaturated esters was obtained from Knoevenagel reaction under very mild conditions cheap reagents.
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