Black-blood T2* technique for myocardial iron measurement in thalassemia.
作者： Taigang He , Peter D. Gatehouse , Paul Kirk , Mark A. Tanner , Gillian C. Smith
DOI: 10.1002/JMRI.20929
关键词: Diastole 、 Pulse (signal processing) 、 Myocardial iron 、 Nuclear medicine 、 Thalassemia 、 Coefficient of variation 、 Black blood 、 Medicine 、 Internal medicine 、 Reproducibility 、 Systole 、 Cardiology
摘要: Purpose To compare the effectiveness and reproducibility of a new black-blood sequence vs. conventional bright-blood gradient-echo T2* for myocardial iron overload measurement in thalassemia. Materials Methods Twenty thalassemia patients were studied. Black-blood images acquired diastole after double inversion recovery (DIR) preparation pulse. Bright-blood both early systole late diastole. The data randomized analysis was performed blindly by two independent observers. Results The values from comparable to those (25.7 ± 12.9 msec 26.4 14.2 systole, P = 0.44; 25.2 13.1 diastole, 0.41). coefficient variation (CV) image 4.1% compared with 8.9% (early 0.03) 7.8% (late 0.05) analysis. Conclusion The technique yields high-contrast images, provides clearly depicted borders, avoids blood signal contamination myocardium while yielding improvements interobserver variability. J. Magn. Reson. Imaging 2007;25:1205–1209. © 2007 Wiley-Liss, Inc.
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