The Diverse Roles of K+Channels in Brain Ischemia
作者： Hiroaki Misonou , James S. Trimmer
DOI: 10.1007/978-1-60761-280-3_12
关键词: BK channel 、 Neuroprotection 、 K channels 、 Neuroscience 、 Katp channels 、 Brain ischemia 、 Ischemic brain 、 Ion channel 、 Chemistry 、 Function (biology)
摘要: K+-selective ion channels are important determinants of neuronal excitability. The activity three particular K+ channels, Kir6.2, Slo1, and Kv2.1, is implicated in neuroprotection ischemic brain neurons. Here we review recent studies on the molecular properties, expression, function these their regulation neurons, potential as drug targets for prophylactic and/or post-event therapeutics.
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