A phase II clinical trial of celecoxib combined with platinum-based regimen as first-line chemotherapy for advanced non-small cell lung cancer patients with cyclooxygenase-2 positive expression

作者: Jun Zhao , Zhi-jie Wang , Jian-chun Duan , Qing-zhi Guo , Hua Bai

DOI: 10.1007/S11670-009-0001-3

关键词: First line chemotherapyCyclooxygenaseClinical trialMedicineNon small cellLung cancerInternal medicineCelecoxibRegimenChemotherapySurgeryOncology

摘要: Objective To evaluate the efficacy and safety of celecoxib plus platinum-doublet as first-line chemotherapy in treatment advanced non-small cell lung cancer (NSCLC), to determine subgroup benefiting from combined therapy by molecular analysis.

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