IL-28, IL-29 and their class II cytokine receptor IL-28R

作者: Paul Sheppard , Wayne Kindsvogel , Wenfeng Xu , Katherine Henderson , Stacy Schlutsmeyer

DOI: 10.1038/NI873

关键词: Interleukin-21 receptorInterleukin-23 receptorCytokine receptorVirologyInterleukin-4 receptorImmunologyInterleukin 28Janus kinase 1Interleukin-6 receptorBiologyCommon gamma chain

摘要: … We found that like type I IFNs, IL-28 and IL-29 were induced by viral infection and showed antiviral activity. However, IL-28 and IL-29 interacted with a heterodimeric class II cytokine …

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