Zinc treatment prevents dysmenorrhea.

摘要: Primary dysmenorrhea, menstrual cramps in otherwise well women, produces mild to debilitating cramping of the uterus. More than half, and by some estimates 90% all American women experience during first several days menstruation. About one ten are unable perform their normal routine for three each cycle due severe uterine cramping. Although uterus contracts relaxes routinely, menstruation contractions much stronger producing pain "cramps". Women with dysmenorrhea have high levels prostaglandins, hormones believed cause Prostaglandins temporarily reduce or stop blood supply uterus, thus depriving oxygen resulting pain. One would expect zinc, like non-steroidal anti-inflammatory drugs used treat cramping, production prostaglandins. Zinc inhibits metabolism prostaglandins ruling out this mechanism action, suggesting erroneously that zinc deficiency prevent However, it is shown case histories 1-3 30-mg doses given daily four prior onset menses, prevents essentially warning menses hypothesis a action precursor (COX-2) metabolite causes not themselves. Another has antioxidant actions Improvement micro-vessel circulation may help In patients consuming 31 mg per day, premenstrual tension (PMT) symptoms did occur, while 15 PMT occur (P<0.001). Protocols using 30 once times day immediately described they recommended additional study. The side effect from absence pending treatment was concern possible pregnancy. United States RDA appears be too low optimize women's health cramps.