Corneal Light Shield as a Delivery System for Standardized Application of Mitomycin C in Excimer Surface Ablation

摘要: PURPOSE To develop a simple, reproducible method of applying intraoperative mitomycin C (MMC) in excimer surface ablation surgery. METHODS A two-part protocol was developed to study several properties corneal light shields. Part tested the amount MMC (0.2 mg/mL) absorbed, expansion dimension attained, and released filter paper. B examined vitro release photorefractive keratectomy (PRK)-treated enucleated pig eye. RESULTS Mean absorbed by shields 63.7 +/- 5.0 mg (range: 57.4 72.8 mg); coefficient variability 7.8%. Expansion diameter thickness were constant at 9.0 mm 1.1 mm, respectively. solution paper 55.4 3.9 51.3 63.5 7.1%. transferred PRK-treated eye 2.3 0.7 3.5 33%. CONCLUSIONS Mitomycin contact area, each shield reproducible. Uniform dimensions theoretically provide uniform distribution MMC. This may allow standardization application ablation.