Risk factors and outcomes associated with vancomycin-resistant Enterococcus faecium and ampicillin-resistant Enterococcus faecalis bacteraemia: A 10-year study in a tertiary-care centre in Mexico City.

作者: José Sifuentes-Osornio , Darwin Lambraño-Castillo , Edgar Ortiz-Brizuela , Andrea Ramírez-Fontes , Yanet Estrella Tovar-Calderón

DOI: 10.1016/J.JGAR.2020.12.005

关键词: Internal medicineEnterococcusTertiary careMedicineLogistic regressionAmpicillinEnterococcus faecalisEnterococcus faeciumAPACHE IICentral venous catheter

摘要: Abstract Objectives We sought to identify risk factors associated with vancomycin-resistant Enterococcus faecium (VRE) and ampicillin-resistant faecalis (ARE) bacteraemia, predictors of 30-day mortality, 90-day recurrence-free survival according resistance. Methods evaluated clinical records patients E. bacteraemia (2007–2017). performed bivariate multivariate logistic regression analyses VRE ARE mortality. A Kaplan–Meier estimate was done. Results identified 192 147 episodes, respectively, which 55.7% were (94% vanA) 12.2% ARE. Factors related previous hospitalisation (aOR, 80.18, 95% CI 1.81–634), history central venous catheter 11.15, 2.48–50.2) endotracheal cannula use 17.91, 1.22–262.82). There higher attributable mortality (28%, 14–68%; P Conclusion History invasive device bacteraemia. APACHE II chemotherapy could not or

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