Preterm-associated visual impairment and estimates of retinopathy of prematurity at regional and global levels for 2010

作者: Hannah Blencowe , Joy E. Lawn , Thomas Vazquez , Alistair Fielder , Clare Gilbert

DOI: 10.1038/PR.2013.205

关键词: Moderate visual impairmentChildhood blindnessGestationRetinopathy of prematurityVisually impairedVisual impairmentPediatricsPremature birthMedicineMeta-analysis

摘要: Retinopathy of prematurity (ROP) is a leading cause potentially avoidable childhood blindness worldwide. We estimated ROP burden at the global and regional levels to inform screening treatment programs, research, data priorities. Systematic reviews meta-analyses were undertaken estimate risk subsequent visual impairment for surviving preterm babies by level neonatal care, access screening, treatment. A compartmental model was used cases numbers visually impaired survivors. In 2010, an 184,700 (uncertainty range: 169,600–214,500) developed any stage ROP, 20,000 (15,500–27,200) whom became blind or severely from further 12,300 (8,300–18,400) mild/moderate impairment. Sixty-five percent those born in middle-income regions; 6.2% (4.3–8.9%) all infants >32-wk gestation. Visual other conditions associated with birth will affect larger Improved including oxygen delivery monitoring, facility settings would reduce number affected ROP. tracking coverage locally adapted screening/treatment programs are urgently required.

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