Proteomics and mass spectrometry for cancer biomarker discovery.
作者： Ming Lu , Kym F Faull , Julian P Whitelegge , Jianbo He , Dejun Shen
DOI: 10.4137/BMI.S0
关键词: Genomics 、 Protein biomarkers 、 Cancer 、 Disease 、 Medicine 、 Early detection 、 Bioinformatics 、 Biomarker discovery 、 Mass spectrometry 、 Proteomics
摘要: Proteomics is a rapidly advancing field not only in the of biology but also translational cancer research. In recent years, mass spectrometry and associated technologies have been explored to identify proteins or set specific given disease, for purpose disease detection diagnosis. Such biomarkers are being investigated samples including cells, tissues, serum/plasma, other types body fluids. When sufficiently refined, proteomic may pave way early individualized therapy cancer. Mass approaches coupled with bioinformatic tools developed biomarker discovery validation. Understanding basic concepts application such technology by investigators accelerate clinical protein management.
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Richard D. Smith, Future directions for electrospray ionization for biological analysis using mass spectrometry BioTechniques. ,vol. 41, pp. 147- 148 ,(2006) , 10.2144/000112217
Hong Wang, Sam Hanash, Intact-protein based sample preparation strategies for proteome analysis in combination with mass spectrometry. Mass Spectrometry Reviews. ,vol. 24, pp. 413- 426 ,(2005) , 10.1002/MAS.20018
K. R. Kozak, M. W. Amneus, S. M. Pusey, F. Su, M. N. Luong, S. A. Luong, S. T. Reddy, R. Farias-Eisner, Identification of biomarkers for ovarian cancer using strong anion-exchange ProteinChips: Potential use in diagnosis and prognosis Proceedings of the National Academy of Sciences of the United States of America. ,vol. 100, pp. 12343- 12348 ,(2003) , 10.1073/PNAS.2033602100
Steven P. Gygi, David K. M. Han, Anne-Claude Gingras, Nahum Sonenberg, Ruedi Aebersold, Protein analysis by mass spectrometry and sequence database searching: tools for cancer research in the post-genomic era. Electrophoresis. ,vol. 20, pp. 310- 319 ,(1999) , 10.1002/(SICI)1522-2683(19990201)20:2<310::AID-ELPS310>3.0.CO;2-M
José Baselga, Luca Gianni, Charles Geyer, Edith A. Perez, Alessandro Riva, Christian Jackisch, Future options with trastuzumab for primary systemic and adjuvant therapy Seminars in Oncology. ,vol. 31, pp. 51- 57 ,(2004) , 10.1053/J.SEMINONCOL.2004.07.022
Shen Hu, Yongming Xie, Prasanna Ramachandran, Rachel R. Ogorzalek Loo, Yang Li, Joseph A. Loo, David T. Wong, Large-scale identification of proteins in human salivary proteome by liquid chromatography/mass spectrometry and two-dimensional gel electrophoresis-mass spectrometry. Proteomics. ,vol. 5, pp. 1714- 1728 ,(2005) , 10.1002/PMIC.200401037
Josep Villanueva, John Philip, Carlos A. Chaparro, Yongbiao Li, Ricardo Toledo-Crow, Lin DeNoyer, Martin Fleisher, Richard J. Robbins, Paul Tempst, Correcting Common Errors in Identifying Cancer-Specific Serum Peptide Signatures† Journal of Proteome Research. ,vol. 4, pp. 1060- 1072 ,(2005) , 10.1021/PR050034B
Arzu Umar, Theo M. Luider, John A. Foekens, Ljiljana Paša-Tolić, NanoLC-FT-ICR MS improves proteome coverage attainable for ~3000 laser microdissected breast carcinoma cells Proteomics. ,vol. 7, pp. 323- 329 ,(2007) , 10.1002/PMIC.200600293
Hongbin Zha, Mark Raffeld, Lu Charboneau, Stefania Pittaluga, Larry W Kwak, Emanuel Petricoin, Lance A Liotta, Elaine S Jaffe, Similarities of prosurvival signals in Bcl-2-positive and Bcl-2-negative follicular lymphomas identified by reverse phase protein microarray Laboratory Investigation. ,vol. 84, pp. 235- 244 ,(2004) , 10.1038/LABINVEST.3700051
Anna E Speers, Benjamin F Cravatt, Profiling Enzyme Activities In Vivo Using Click Chemistry Methods Chemistry & Biology. ,vol. 11, pp. 535- 546 ,(2004) , 10.1016/J.CHEMBIOL.2004.03.012