Early recovery of left ventricular function after thrombolytic therapy for acute myocardial infarction: an important determinant of survival.

作者: Florence H. Sheehan , Rolf Doerr , Wolfgang G. Schmidt , Edward L. Bolson , Rainer Uebis

DOI: 10.1016/0735-1097(88)90397-X

关键词: StreptokinaseCardiologyMedicineMyocardial infarctionEjection fractionHemodynamicsEarly recoveryPeripheralInternal medicineVentricular functionChemotherapy

摘要: Abstract Thrombolytic therapy for acute myocardial infarction reduces early mortality, but full recovery of left ventricular function after reperfusion is delayed. Therefore, the relations among reperfusion, survival and time course functional were examined in 226 patients treated with intracoronary streptokinase; 77% (134 patients) had sustained 31 bo or reocclusion by day 3. Wall motion was measured from contrast ventriculograms performed period 3 days later central peripheral infant regions noninfarct region centerline method 165 patients. Patients better (p Although, as previously reported, >45% total occurs later, ejection fraction achieved already predictive survival. Thus, mechanism which successful thrombolytic enhances improvement regional global infarction.

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