Head and neck hemangiomas of infancy.

作者: Carol J MacArthur

DOI: 10.1097/MOO.0B013E328010BA6B

关键词: HemangiomaPediatricsTreatment optionsHead and neckTurn offMedicineBenign tumorClassification schemeIncreased risk

摘要: PURPOSE OF REVIEW Hemangiomas are the most common benign tumor in infancy, affecting approximately 10% of infants. More than half hemangiomas involve head and neck. Increased understanding has come about from identification immunohistochemical markers, developmental defects associated with certain hemangiomas, morphologic classification schemes (focal versus segmental). RECENT FINDINGS Immunohistochemical markers have been identified which specific to all phases development involution. Morphologic subtypes anatomic locations that place an infant at higher risk for complications hemangioma. other anomalies identified, help guide treating physician tease out infants will need more complete systemic investigations or imaging. Importantly surgeons, studies continued identify lesions may benefit early intervention, either surgical medical. SUMMARY While full mechanisms turn on off infancy is not complete, progress made increased complications, treatment. With work these areas, we knowledge treatment options, optimal timing ultimately, preventive options.

参考文章(30)
Mulliken Jb, Enjolras O, Vascular tumors and vascular malformations (new issues). Advances in Dermatology. ,vol. 13, pp. 375- 423 ,(1997)
Seth J. Orlow, Michael S. Isakoff, Francine Blei, Increased risk of symptomatic hemangiomas of the airway in association with cutaneous hemangiomas in a “beard” distribution The Journal of Pediatrics. ,vol. 131, pp. 643- 646 ,(1997) , 10.1016/S0022-3476(97)70079-9
Mark Very, Mark Nagy, Michelle Carr, Sandy Collins, Linda Brodsky, Hemangiomas and vascular malformations: Analysis of diagnostic accuracy Laryngoscope. ,vol. 112, pp. 612- 615 ,(2002) , 10.1097/00005537-200204000-00004
John B. Mulliken, Julie Glowacki, Hemangiomas and Vascular Malformations in Infants and Children Plastic and Reconstructive Surgery. ,vol. 69, pp. 412- 420 ,(1982) , 10.1097/00006534-198203000-00002
Reza Rahbar, Richard Nicollas, Gilles Roger, Jean-Michel Triglia, Erea-Noel Garabedian, Trevor J. McGill, Gerald B. Healy, The biology and management of subglottic hemangioma: past, present, future. Laryngoscope. ,vol. 114, pp. 1880- 1891 ,(2004) , 10.1097/01.MLG.0000147915.58862.27
Mark A. Bittles, Manrita K. Sidhu, Raymond W. Sze, Laura S. Finn, Victor Ghioni, Johnathan A. Perkins, Multidetector CT angiography of pediatric vascular malformations and hemangiomas: utility of 3-D reformatting in differential diagnosis Pediatric Radiology. ,vol. 35, pp. 1100- 1106 ,(2005) , 10.1007/S00247-005-1553-0
Jiad N. Mcheik, Vincent Renauld, Gerard Duport, Pierre Vergnes, Guillaume Levard, Surgical treatment of haemangioma in infants British Journal of Plastic Surgery. ,vol. 58, pp. 1067- 1072 ,(2005) , 10.1016/J.BJPS.2005.04.029
Jaime Perez, José Pardo, Cristina Gomez, Vincristine--An Effective Treatment of Corticoid-resistant Life-threatening Infantile Hemangiomas Acta Oncologica. ,vol. 41, pp. 197- 199 ,(2002) , 10.1080/028418602753669607
Camille Haisley-Royster, Odile Enjolras, Ilona J. Frieden, Maria Garzon, Margaret Lee, Peter C.J. de Laat, Gerard C. Madern, Francisco Gonzalez, Hayder Frangoul, Philippe Le Moine, Neil S. Prose, Denise M. Adams, Kasabach-merritt phenomenon: a retrospective study of treatment with vincristine. Journal of Pediatric Hematology Oncology. ,vol. 24, pp. 459- 462 ,(2002) , 10.1097/00043426-200208000-00010
Anita N Haggstrom, Edward J Lammer, Richard A Schneider, Ralph Marcucio, Ilona J Frieden, Patterns of infantile hemangiomas: new clues to hemangioma pathogenesis and embryonic facial development. Pediatrics. ,vol. 117, pp. 698- 703 ,(2006) , 10.1542/PEDS.2005-1092