Postoperative Analgesia in Children After Propofol Versus Sevoflurane Anesthesia

作者: Antigona Hasani , Agreta Gecaj-Gashi , Sadik Llullaku , Hysni Jashari

DOI: 10.1111/PME.12031

关键词: FentanylAnesthesiaPropofolBupivacaineMedicineSurgeryPain scaleAcetaminophenAdverse effectSevofluraneSurgical incision

摘要: Objective Postoperative analgesia remains a problem, especially in pediatric patients. We hypothesize that patients anesthetized with sevoflurane have more postoperative pain than propofol. Design Randomized, prospective, double-blind study. Setting University teaching hospital. Subjects The subjects were 88 premedicated children, aged 3–6 years, and American Society of Anesthesiologists (ASA) Physical Status I or II. Interventions Subjectsunderwent hernia repair surgery. Methods Anesthesia was maintained propofol (group P, N = 46) S, 42) fentanyl administered during surgery. All children before surgical incision received 40 mg/kg paracetamol, rectally. Prior to wound closure, the margins infiltrated 0.5% bupivacaine. Outcome Measures primary outcome score assessed by Faces Pain Scale (FPS) 2 hours postoperatively. secondary outcomes included recovery time adverse events within first hours. Results Group S had significantly higher proportion who exhibited group P (24.3% vs 4.5%, respectively; < 0.05). FPS 1.2 ± 0.6, compared 3.4 1.5 ( 0.001). Mean shorter corresponding mean for (10.1 1.3 16.5 5.4 minutes, 0.001). Conclusion In anesthesia maintenance associated lower incidence sevoflurane.

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