Cancer risk of petrochemical workers exposed to airborne PAHs in industrial Lanzhou City, China

作者: Li Wang , Yuan Zhao , Xianying Liu , Tao Huang , Yanan Wang

DOI: 10.1007/S11356-015-5203-2

关键词: Health riskCancer riskWaste managementRisk levelExposure levelOffice workersInhalation exposureTissue distributionMedicineEnvironmental healthPetrochemical

摘要: This paper reports the connections between red blood cells abnormality risk of petrochemical workers and their exposure to airborne polycyclic aromatic hydrocarbons (PAHs). Urinary 1-hydroxypyrene (1-OHP), as biomarker PAHs exposure, was adopted assess in Xigu, west suburb Lanzhou where industries are located. Fifty-three workers, sub-grouped 36 17 office participated this investigation. Logistic regression model spearman correlation analysis were performed estimate associations levels workers. Strong some cell indices (MCH, MCHC, RDW) 1-OHP concentration found. Results also show that increased with increasing level. Compared level higher by 41.7 % (OR, 1.417; 95 CI: 0.368-5.456) than result verified tissue-to-human partition coefficient for pyrene 1-OHP. The quantitative assessments potential health through inhalation conducted using Incremental Lifetime Cancer Risk (ILCR) model. It found ILCR from ranged 10(-5) 10(-4) probability, indicating plant under a high cancer

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