作者: Morten Gersel Stokholm , Carsten Bisgård , Ole Jakob Vilholm
DOI: 10.3109/21678421.2013.830312
关键词: Feeding tube 、 Amyotrophic lateral sclerosis 、 Botulinum neurotoxin 、 Physical therapy 、 MEDLINE 、 Tailored treatment 、 Intensive care medicine 、 Drooling 、 Medicine 、 Personalized treatment 、 Adverse effect
摘要: Botulinum neurotoxin (BoNT) is a second-line treatment of sialorrhoea in ALS (amyotrophic lateral sclerosis) patients. This article review the published literature concerning safety and administration this to A PubMed search was performed. All original publications on BoNT patients were included review. Only few adverse events observed with BoNT. The studies performed date have applied different strategies dosages. In conclusion, for safe effects. authors advocate implementation personalized strategy. Special precautions must be taken when do not assistance ventilator feeding tube.