Unprecedented route to enolates from silyl enol ethers and enol acetates: reaction with hard and soft electrophiles
作者： Pierre Duhamel , Dominique Cahard , Jean-Marie Poirier
DOI: 10.1039/P19930002509
关键词: Benzaldehyde 、 Alkoxide 、 Electrophile 、 Organic chemistry 、 Aldol condensation 、 Chemistry 、 Enol ether 、 Ether 、 Enol 、 Silylation
摘要: Reaction of silyl enol ethers with lithium, sodium or, better, potassium alkoxides resulted in a rapid formation enolates which were trapped hard electrophiles and benzaldehyde. Moreover, the aldolisation reaction, only catalytic amount alkali alkoxide is needed. This methodology also applied to acetate. During these reactions non-basic species, ether or ester, produced enolate.
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