The level of urinary α1 microglobulin excretion is a useful marker of peritubular capillaritis in antineutrophil cytoplasmic antibody associated vasculitis

作者: Naro Ohashi , Sayaka Ishigaki , Kazuto Kitajima , Naoko Tsuji , Shinsuke Isobe

DOI: 10.1007/S10157-014-1073-Z

关键词: Anti-neutrophil cytoplasmic antibodyExcretionBeta-2 microglobulinPathologyInternal medicineKidneyMedicineUrinary systemNephrologyVasculitisPeritubular capillariesImmunology

摘要: Background Antineutrophil cytoplasmic antibody (ANCA) associated vasculitis affects small vessels in the kidney (i.e., arterioles, glomerular or peritubular capillaries, venules). Although crescentic glomerulonephritis is a common histological finding, incidence of capillaritis (PTC) arteriolitis unclear. Moreover, laboratory data that reflect degree renal damage and distinguish between PTC have not yet been clarified.

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