Relevance of Tumor-Infiltrating Immune Cell Composition and Functionality for Disease Outcome in Breast Cancer.

作者: Rico D. Bense , Christos Sotiriou , Martine J. Piccart-Gebhart , John B. A. G. Haanen , Marcel A. T. M. van Vugt

DOI: 10.1093/JNCI/DJW192

关键词: Internal medicineSurvival rateImmunologyTrastuzumabAdjuvant therapyOncologyBreast cancerEstrogen receptorHazard ratioImmunotherapyNeoadjuvant therapyMedicine

摘要: … toward either the M1 or M2 macrophage subtypes. The hypothesis that M0 macrophage fraction seems relevant in both OS and DFS underlines its possible impact on intrinsic ER-…

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