Human Tumor-Derived p53 Mutants: A Growing Family of Oncoproteins

Dakang Xu, Trevor J Wilson, David Chan, Elisabetta De Luca, Jiong Zhou, Paul J Hertzog, Ismail Kola, Ets1 is required for p53 transcriptional activity in UV-induced apoptosis in embryonic stem cells The EMBO Journal. ,vol. 21, pp. 4081- 4093 ,(2002) , 10.1093/EMBOJ/CDF413

Fabio Valenti, Francesca Fausti, Francesca Biagioni, Tal Shay, Giulia Fontemaggi, Eytan Domany, Michael B. Yaffe, Sabrina Strano, Giovanni Blandino, Silvia Di Agostino, Mutant p53 oncogenic functions are sustained by Plk2 kinase through an autoregulatory feedback loop Cell Cycle. ,vol. 10, pp. 4330- 4340 ,(2011) , 10.4161/CC.10.24.18682

Claudia Fiorini, Marco Cordani, Chiara Padroni, Giovanni Blandino, Silvia Di Agostino, Massimo Donadelli, Mutant p53 stimulates chemoresistance of pancreatic adenocarcinoma cells to gemcitabine. Biochimica et Biophysica Acta. ,vol. 1853, pp. 89- 100 ,(2015) , 10.1016/J.BBAMCR.2014.10.003

Patricia A. J. Muller, Karen H. Vousden, p53 mutations in cancer Nature Cell Biology. ,vol. 15, pp. 2- 8 ,(2013) , 10.1038/NCB2641

Nathan D. Camp, Richard G. James, David W. Dawson, Feng Yan, James M. Davison, Scott A. Houck, Xiaobo Tang, Ning Zheng, Michael B. Major, Randall T. Moon, Wilms Tumor Gene on X Chromosome (WTX) Inhibits Degradation of NRF2 Protein through Competitive Binding to KEAP1 Protein Journal of Biological Chemistry. ,vol. 287, pp. 6539- 6550 ,(2012) , 10.1074/JBC.M111.316471

Carolyn Y. Zhao, Vera Grinkevich, Fedor Nikulenkov, Wenjie Bao, Galina Selivanova, Rescue of the apoptotic-inducing function of mutant p53 by small molecule RITA Cell Cycle. ,vol. 9, pp. 1847- 1855 ,(2010) , 10.4161/CC.9.9.11545

Tiziana Bruno, Agata Desantis, Gianluca Bossi, Silvia Di Agostino, Cristina Sorino, Francesca De Nicola, Simona Iezzi, Annapaola Franchitto, Barbara Benassi, Sergio Galanti, Francesca La Rosa, Aristide Floridi, Alfonso Bellacosa, Claudio Passananti, Giovanni Blandino, Maurizio Fanciulli, Che-1 Promotes Tumor Cell Survival by Sustaining Mutant p53 Transcription and Inhibiting DNA Damage Response Activation Cancer Cell. ,vol. 18, pp. 122- 134 ,(2010) , 10.1016/J.CCR.2010.05.027

Yang Xu, Jin Zhang, Xinbin Chen, The activity of p53 is differentially regulated by Brm- and Brg1-containing SWI/SNF chromatin remodeling complexes. Journal of Biological Chemistry. ,vol. 282, pp. 37429- 37435 ,(2007) , 10.1074/JBC.M706039200

M H Stindt, P A J Muller, R L Ludwig, S Kehrloesser, V Dötsch, K H Vousden, Functional interplay between MDM2, p63/p73 and mutant p53 Oncogene. ,vol. 34, pp. 4300- 4310 ,(2015) , 10.1038/ONC.2014.359

Vladimir J.N. Bykov, Natalia Issaeva, Alexandre Shilov, Monica Hultcrantz, Elena Pugacheva, Peter Chumakov, Jan Bergman, Klas G. Wiman, Galina Selivanova, Restoration of the tumor suppressor function to mutant p53 by a low-molecular-weight compound Nature Medicine. ,vol. 8, pp. 282- 288 ,(2002) , 10.1038/NM0302-282