Antimicrobial properties of novel n-halamine siloxane coatings

作者: JF Williams , J Suess , J Santiago , Y Chen , J Wang

DOI: 10.1007/BF02699705

关键词: Filter mediaSiloxaneOrganic chemistryChloramineBiocideLimitingCombinatorial chemistryContaminationMaterials scienceAntimicrobialFood service

摘要: Antimicrobial coatings on a wide variety of hard and soft substrates were prepared by exposing surfaces treated with novel N-halamine siloxane precursor monomers macro-monomers to oxidative halogen solutions. Suspensions range bacterial, viral, fungal yeast micro-organisms applied the halogen-charged for defined intervals, before recovery quantification surviving microbes using appropriate neutralisation culture techniques. The biocidal exhibited powerful, broad-spectrum antimicrobial properties, inactivating most challenge in contact times measured minutes hours, rather than extended incubation periods usually associated substrate-bound agents. effects also demonstrated prevent odour caused bacterial generation ammonia an experimental simulation urine-soaked nappy pad. Contact efficacy related bound concentrations per unit surface area. Potential benefits these rechargeable cover range, from limiting contamination environmental disease agents healthcare or food service facilities, controlling mildew bathrooms, preventing formation incontinence pads. They confer protective functions textiles non-woven filter media air water.

参考文章(12)
S. D. Worley, Y. Chen, J. -W. Wang, R. Wu, U. Cho, R. M. Broughton, J. Kim, C. -I. Wei, J. F. Williams, J. Chen, Y. Li, Novel N-halamine siloxane monomers and polymers for preparing biocidal coatings Surface Coatings International Part B-coatings Transactions. ,vol. 88, pp. 93- 99 ,(2005) , 10.1007/BF02699539
Jacques E. Elfersy, Joachim Berkner, Timothy C. Moses, Water-stabilized organosilane compounds and methods for using the same ,(1998)
Yongjun Chen, S. D. Worley, Jangho Kim, C.-I. Wei, Tay-Yuan Chen, J. I. Santiago, J. F. Williams, Gang Sun, Biocidal Poly(styrenehydantoin) Beads for Disinfection of Water Industrial & Engineering Chemistry Research. ,vol. 42, pp. 280- 284 ,(2003) , 10.1021/IE020266+
Sarah Slaughter, Mary K Hayden, Catherine Nathan, Tzyy-Chyn Hu, Thomas Rice, Jean Van Voorhis, Marian Matushek, Cory Franklin, Robert A Weinstein, A Comparison of the Effect of Universal Use of Gloves and Gowns with That of Glove Use Alone on Acquisition of Vancomycin-Resistant Enterococci in a Medical Intensive Care Unit Annals of Internal Medicine. ,vol. 125, pp. 448- 456 ,(1996) , 10.7326/0003-4819-125-6-199609150-00004
M.W. Eknoian, S.D. Worley, J. Bickert, J.F. Williams, Novel antimicrobial N-halamine polymer coatings generated by emulsion polymerization Polymer. ,vol. 40, pp. 1367- 1371 ,(1999) , 10.1016/S0032-3861(98)00383-8
JEFFREY F. WILLIAMS, S. DAVID WORLEY, Infection-resistant nonleachable materials for urologic devices Journal of Endourology. ,vol. 14, pp. 395- 400 ,(2000) , 10.1089/END.2000.14.395
Stuart B. Levy, Antibacterial household products: cause for concern. Emerging Infectious Diseases. ,vol. 7, pp. 512- 515 ,(2001) , 10.3201/EID0707.017705
M. W. Eknoian, J. H. Putman, S. D. Worley, Monomeric and Polymeric N-Halamine Disinfectants Industrial & Engineering Chemistry Research. ,vol. 37, pp. 2873- 2877 ,(1998) , 10.1021/IE970943D
R. V Tauxe, J. M Hughes, International investigation of outbreaks of foodborne disease BMJ. ,vol. 313, pp. 1093- 1094 ,(1996) , 10.1136/BMJ.313.7065.1093
Samuel P. Sawan, Alexander Yurkovetskiy, Sundar Subramanyam, Tadmor Shalon, Contact-killing non-leaching antimicrobial materials ,(1997)