Variations in Brain Gray Matter Associated with Chronic Pain

作者: Patrick B. Wood

DOI: 10.1007/S11926-010-0129-7

关键词: Physical therapyClinical psychologyChronic low back painRheumatologyInternal medicineIrritable bowel syndromeBrain Gray MatterBrain morphometryChronic painFibromyalgiaVoxel-based morphometryMedicine

摘要: Variations in brain gray matter volume and density have been reported association with a variety of disorders characterized by chronic pain, including low back fibromyalgia, irritable bowel syndrome. Correlation analyses demonstrated relationships between morphometric clinical variables. However, conclusions regarding the nature these are problematic given that currently available data derived exclusively from cross-sectional studies. Further efforts to determine relationship pain variations morphometry will depend part on longitudinal studies patients at various stages illness, as well those risk development pain. Interpretation findings also must take into account genetic experiential factors recently influence developing

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