Genotoxicity analysis and hazardousness prioritization of a group of chemicals
作者： E. Degirmenci , Y. Ono , O. Kawara , H. Utsumi
关键词: Prioritization 、 Chemistry 、 Chemical compound 、 Waste management 、 Bioconcentration 、 Environmental chemistry 、 Safety testing 、 Investigation methods 、 Genotoxicity 、 Sorption coefficient
摘要: Genotoxic chemicals are increasingly being used in our daily life. 180-chemicals were screened to identify the priority of hazardousness from point view their genotoxicity. Umu -test was evaluate genotoxicity these chemicals. Some exhibited high genotoxic response. A scoring algorithm developed level based on and four other characteristics: biodegradation probability, soil adsorption coefficient, (KOC), bioconcentration factor (BCF), Henry9s Law constant (HLC). Then, sorted a descending order probability.
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