Implication of RNA structure on antisense oligonucleotide hybridization kinetics.
作者： Walt F. Lima , Brett P. Monia , David J. Ecker , Susan M. Freier
DOI: 10.1021/BI00163A013
关键词: Nucleic acid structure 、 Protein secondary structure 、 Biophysics 、 RNA 、 Messenger RNA 、 Nucleic acid thermodynamics 、 Biology 、 Antisense RNA 、 Molecular biology 、 Oligonucleotide 、 Gene
摘要: … and a complementary single-stranded RNA 10-mer. Association … better than 2-fold, the plot in Figure 3D and the kinetic data … Effects of Structure on Hybridization Kinetics. Data in Table II …
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