Blood transfusion does not affect survival of gastric cancer patients.

作者: Jingli Cui , Jingyu Deng , Xuewei Ding , Li Zhang , Rupeng Zhang

DOI: 10.1016/J.JSS.2015.07.019

关键词: GastroenterologySurvival analysisRetrospective cohort studyBlood transfusionInternal medicineSurgeryHazard ratioGastrectomySurvival rateCancerMedicinePerioperative

摘要: Abstract Background To initially assess the impact of perioperative blood transfusions (PBTs) on overall survival patients underwent curative resection Ⅰ–Ⅲ TNM stage gastric cancer (GC) using propensity scoring method. Methods The medical records 1150 GC who in Tianjin Cancer Hospital between 2003 and 2008 were retrospectively analyzed. Both transfusion nontransfusion assessed prognostic differences after surgery score analysis. Results A total 299 (26.0%) administrated PBT. With unadjusted analysis, with PBT presented older age, more operative loss, lower hemoglobin, albumin level, higher risk advanced disease. 5-y rate for was 31.0%, which significantly than that (47.9%) without (P   0.05). In addition, we also found not associated increasing mortality (hazard ratio, 1.054; P = 0.628). Conclusions could give rise to worse prognoses patients.

参考文章(22)
Tze Yeng Yeoh, Federica Scavonetto, Toby N. Weingarten, R. Jeffrey Karnes, Camille M. van Buskirk, Andrew C. Hanson, Darrell R. Schroeder, Juraj Sprung, Perioperative allogeneic nonleukoreduced blood transfusion and prostate cancer outcomes after radical prostatectomy Transfusion. ,vol. 54, pp. 2175- 2181 ,(2014) , 10.1111/TRF.12595
Toshiyasu Ojima, Makoto Iwahashi, Mikihito Nakamori, Masaki Nakamura, Teiji Naka, Masahiro Katsuda, Takeshi Iida, Keiji Hayata, Hiroki Yamaue, Association of Allogeneic Blood Transfusions and Long-Term Survival of Patients with Gastric Cancer after Curative Gastrectomy Journal of Gastrointestinal Surgery. ,vol. 13, pp. 1821- 1830 ,(2009) , 10.1007/S11605-009-0973-9
Sunao Moriguchi, Yoshihiko Maehara, Kouhei Akazawa, Keizo Sugimachi, Yoshiaki Nose, Lack of relationship between perioperative blood transfusion and survival time after curative resection for gastric cancer Cancer. ,vol. 66, pp. 2331- 2335 ,(1990) , 10.1002/1097-0142(19901201)66:11<2331::AID-CNCR2820661113>3.0.CO;2-H
Joris J. Harlaar, Martijn P. Gosselink, Wim C. J. Hop, Johan F. Lange, Olivier R. C. Busch, Hans Jeekel, Blood transfusions and prognosis in colorectal cancer: long-term results of a randomized controlled trial Annals of Surgery. ,vol. 256, pp. 681- 687 ,(2012) , 10.1097/SLA.0B013E318271CEDF
Woo Jin Hyung, Sung Hoon Noh, Dong Woo Shin, Ji Hun J. Huh, Bong J. Huh, Seung Ho Choi, Jin Sik Min, Adverse effects of perioperative transfusion on patients with stage III and IV gastric cancer Annals of Surgical Oncology. ,vol. 9, pp. 5- 12 ,(2002) , 10.1245/ASO.2002.9.1.5
Steven C. Katz, Jinru Shia, Kui Hin Liau, Mithat Gonen, Leyo Ruo, William R. Jarnagin, Yuman Fong, Michael I. DʼAngelica, Leslie H. Blumgart, Ronald P. DeMatteo, Operative blood loss independently predicts recurrence and survival after resection of hepatocellular carcinoma. Annals of Surgery. ,vol. 249, pp. 617- 623 ,(2009) , 10.1097/SLA.0B013E31819ED22F
Yoshihiro Komatsu, Hajime Orita, Mutsumi Sakurada, Hiroshi Maekawa, Toshitaka Hoppo, Koichi Sato, Intraoperative Blood Transfusion Contributes to Decreased Long-Term Survival of Patients With Esophageal Cancer World Journal of Surgery. ,vol. 36, pp. 844- 850 ,(2012) , 10.1007/S00268-012-1433-3
Morris A. Blajchman, Immunomodulation and blood transfusion. American Journal of Therapeutics. ,vol. 9, pp. 389- 395 ,(2002) , 10.1097/00045391-200209000-00005
Bruno Zilberstein, Carlos Eduardo Jacob, Ivan Cecconello, Gastric cancer trends in epidemiology. Arquivos De Gastroenterologia. ,vol. 49, pp. 177- 178 ,(2012) , 10.1590/S0004-28032012000300001
Shintaro Kuroda, Hirotaka Tashiro, Tsuyoshi Kobayashi, Akihiko Oshita, Hironobu Amano, Hideki Ohdan, No Impact of Perioperative Blood Transfusion on Recurrence of Hepatocellular Carcinoma after Hepatectomy World Journal of Surgery. ,vol. 36, pp. 651- 658 ,(2012) , 10.1007/S00268-012-1425-3