Diagnostic Performance of Blood Pressure Measurement Modalities in Living Kidney Donor Candidates.

摘要: Background and objectives Precise BP measurement to exclude hypertension is critical in evaluating potential living kidney donors. Ambulatory monitoring considered the gold standard method for diagnosing hypertension, but it cumbersome perform. We sought determine whether lower cutoffs using office automated would reduce rate of missed Design, setting, participants, & measurements measured 578 prospective donors three modalities: (1) single BP, (2) (average five consecutive readings separated by 1 minute), (3) ambulatory BP. Daytime was hypertension. assessed both Seventh Report Joint National Committee on Prevention, Detection, Evaluation, Treatment High Blood Pressure (JNC-7) American College Cardiology/American Heart Association (ACC/AHA) definitions cohort. Empirical thresholds detection BP–diagnosed were derived Youden index, which maximizes sum sensitivity specificity gives equal weight false positive negative values. Results Hypertension diagnosed 90 (16%) JNC-7 criteria 198 (34%) ACC/AHA criteria. Masked found 3% total cohort combination or seen 24% guidelines. Using ( Conclusions The prevalence higher donor candidates compared definitions. Lower clinic improved led a low overall