Epileptic disorders with onset in the first year of life: neurological and cognitive outcome

作者: D. Battaglia , T. Randó , F. Deodato , G. Bruccini , G. Baglio

DOI: 10.1016/S1090-3798(99)90096-X

关键词: PediatricsFamily historyAge of onsetFirst year of lifeMedicineEpilepsyCognitionWest SyndromeEtiologyPsychomotor learning

摘要: We examined prospectively a series of 150 children with epilepsy beginning in the first year life. classified types into five categories: West syndrome, other epileptic encephalopathies, generalized, partial and undetermined epilepsies. Of patients, 15 died; 135 were followed for at least 4 years. In order to define possible factors influencing prognosis we evaluated neurological cognitive outcome made percentage comparisons between groups, aetiology, age onset, family history epilepsy, psychomotor development before onset. Epileptic encephalopathies as well symptomatic forms syndrome showed very poor outcome. As previously recognized, only cryptogenic had benign prognosis. For generalized epilepsies, analysis different factors, namely late cryptogenicity absence primary impairment, indicated good contrast, epilepsies usually outcome, irrespective whether or symptomatic.

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