作者: Jacob S. Margolis , Katrina Abuabara , Warren Bilker , Ole Hoffstad , David J. Margolis
DOI: 10.1001/JAMADERMATOL.2013.10271
关键词: Prospective cohort study 、 Observational study 、 Severity of illness 、 Medicine 、 Young adult 、 Pediatrics 、 MEDLINE 、 Cohort study 、 Natural history 、 Atopic dermatitis
摘要: Importance Atopic dermatitis (AD) is a common illness of childhood. Objective To evaluate the natural history AD and determine persistence symptoms over time. Design, Setting, Participants A cross-sectional cohort study nation-wide long-term registry children with enrolled in Pediatric Eczema Elective Registry (PEER). Main Outcomes Measures Self-reported outcome whether child’s skin was symptom–free for 6 months at 6-month intervals. Results total 7157 patients were PEER 22 550 person-years. At least 2 years follow-up observed 4248 5 2416 children. Multiple demographic exposure variables associated more persistent AD. every age (ie, 2-26 years), than 80% participants had and/or using medication to treat their It not until 20 that 50% 1 lifetime symptom- treatment-free period. Conclusions Relevance Based on this large longitudinal study, seem persist well into second decade life likely longer. probably life-long illness.