Aldosterone-to-renin ratio and nocturnal blood pressure decline assessed by self-measurement of blood pressure at home: The Ohasama Study

作者: Michihiro Satoh , Miki Hosaka , Kei Asayama , Masahiro Kikuya , Ryusuke Inoue

DOI: 10.3109/10641963.2014.892121

关键词: Odds ratioAldosterone-to-renin ratioPlasma renin activityPopulationBlood pressureEndocrinologyInternal medicineMorningAmbulatory blood pressureMedicineCardiologyAldosterone

摘要: AbstractBased on ambulatory blood pressure (BP) monitoring, the aldosterone-to-renin ratio (ARR) has been reported to be associated with a diminished nocturnal decline in BP, generally referred as “non-dipping” pattern. The objective of this cross-sectional study was investigate association between ARR and non-dipping pattern based home BP measurements. This included 177 participants ≥55 years from general population Ohasama (mean age: 67.2 years; 74.6% women); no patient receiving antihypertensive treatment. median plasma renin activity (PRA), aldosterone concentration (PAC) were 0.8 ng/mL/h, 8.1 ng/dL 9.7 ng/dL per ng/mL/h, respectively. Each 1 SD increase log-transformed (ln) significantly prevalence after adjustments for possible confounding factors including morning systolic (odds ratio, 1.45; p = 0.049). However, significant associations PRA or PAC p...

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