Acute toxicological studies of the main organosulfur compound derived from Allium sp. intended to be used in active food packaging.
作者： María Llana-Ruiz-Cabello , Daniel Gutiérrez-Praena , María Puerto , Silvia Pichardo , F. Javier Moreno
DOI: 10.1016/J.FCT.2015.04.027
关键词: Cytotoxicity 、 Preservative 、 Biotechnology 、 Antioxidant 、 Antimicrobial 、 Chemistry 、 Food science 、 Organosulfur compounds 、 Food industry 、 Allium 、 Food packaging
摘要: Some plant extracts have been proposed as potential alternative to the use of synthetic preservatives in food industry. Among those, from Allium species exhibit interesting antimicrobial and antioxidant properties for packaging The present work aims assess usefulness safety major organosulfur compound a commercial sp. extract (PROALLIUM AP®), namely propyl thiosulfinate oxide (PTSO). For this purpose, its activity was studied wide range microorganisms. Moreover, cytotoxicity ultrastructural cellular damages caused by PTSO were two human cell lines, Caco-2 HepG2, being colonic cells more sensitive compound. Finally, protective role against an induced oxidative situation evaluated intestinal cells. results revealed damage at high concentration, although no significant adverse effects recorded concentration be used packaging. vivo study also established concentrations. In addition, confirmed. Therefore, could considered good natural
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