Is the future for clinical trials internet-based? A cluster randomized clinical trial.

摘要: Objective To compare the efficiency and ease of use internet data capture compared with conventional paper based recording in conduct a clinical trial.Design Multicentre, cluster randomized trial.Setting General practice UK.Main outcome measures Timings for study landmarks, queries, entry monitoring time; Investigator Questionnaire Results.Results The internet-derived database was ready release 33 days after last patient visit 48 paper-derived database, despite much higher numbers patients group. mean times from to were 10.2 (SD 18.9) 95.4 44.6) respectively (P, 0.01). query being resolved 121.4 58.3) 182.1 58.9) post-study responses investigators positive. Seventy-one percent centressaid they would prefer rather than CRFs future studies.Conclusi...